Jarish N. Cohen, MD, PhD

I am a physician-scientist who investigates the immunologic basis of inflammatory dermatoses and autoimmune alopecias. My lab gleans mechanistic insights into the complex interplay between the adaptive and innate immune system and epithelial stem cells in the skin. The lab utilizes a novel technique to manipulate immune cells in a skin-specific manner with innovative experimental models of autoimmune alopecia to uncover mechanisms of epithelial stem cell loss and immunoregulatory dysfunction. We translate our findings in the context of human dermatoses and alopecias by leveraging patient-derived, archival material for multiomics studies (e.g. snFFPEseq and spatial transcriptomics).

My clinical interests are wide-ranging and include the genetics of heavily pigmented melanocytic neoplasms and cutaneous soft tissue tumors, as well as characterizing the immunophenotypic landscape of inflammatory skin diseases.