Arun P. Wiita, MD, PhD

Arun P. Wiita, MD, PhD

Assistant Professor
Laboratory Medicine
Division
Cytogenetics Laboratory

UCSF
Laboratory Medicine, Box 0134
185 Berry Street, Suite 290
San Francisco, CA 94143
United States

Hospital Affiliations
UCSF Parnassus Heights
Other UCSF Organizational Association(s)

UCSF Cancer Center

Research and Clinical Interests

My research laboratory is focused on understanding fundamental protein translation as well as chemotherapeutic response in hematologic malignancies. We use a combination of deep sequencing of nucleic acids and mass spectrometry-based proteomics to characterize cellular-wide phenotypes in these diseases.

Selected Publications
  • Perez-Jimenez, R., Wiita, A.P., Larrea-Rodriguez, D., Kosuri, P., Gavira, J.A., Sanchez-Ruiz, J.M., and Fernandez, J.M. Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis. J. Biol. Chem. 283, 27121-27129 (2008).
  • Wiita, A.P., Roubinian, N., Khan, Y., Chin-Hong, P.V., Golden, J.A., and Miller, S. Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis. Transpl. Infect. Dis. 14, 248-58 (2012). PMID: 22385394.
  • Wiita, A.P., Nambiar A. Longitudinal management with crossmatch-compatible platelets for refractory patients: alloimmunization, response to transfusion, and clinical outcomes. Transfusion 52, 2146-54 (2012).
  • Wiita, A.P., Ziv, E., Wiita, P.J., Urisman, A., Julien, O., Burlingame, A.L., Weissman, J.S., and Wells, J.A. Global cellular response to chemotherapy-induced apoptosis. eLife 02:e01236 (2013).
  • Wiita, A.P., Hsu, G.W., Lu, C.M., Esensten, J., and Wells, J.A. Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling. Proc. Natl. Acad. Sci. USA 111, 7594-9 (2014).
Awards
  • 2002 Sigma Xi honor society, Princeton U.
  • 2002 Phi Beta Kappa honor society, Princeton U.
  • 2002 Sigma Xi Book Award for undergraduate thesis research, Princeton U.
  • 2008 Winner, Wharton Venture Award, team Bayesian Diagnosis, U. Penn.
  • 2008 Dean's Award for Excellence in Research, Columbia U. College of P&S
  • 2012-14 Damon Runyon Cancer Research Foundation Post-doctoral Fellowship
  • 2014-19 NIH-NCI K08 Mentored Clinical Scientist Development Award
  • 2014 Dale Frey Breakthrough Award, Damon Runyon Cancer Research Foundation