Rama Yakubu, MD, PhD
Assistant Professor
Laboratory Medicine
Division
Microbiology
Specialty Areas
Bacteriology
Virology
UCSF
Laboratory Medicine
185 Berry Street, Suite 290
San Francisco, CA 94107
United States
Other UCSF Organizational Association(s)
Clinical Laboratories at China Basin
Research and Clinical Interests
My research and academic interests lie in the field of molecular parasitology, with a focus on post-translational modifications in Toxoplasma gondii, the development of mass spectrometry methods adapted for the clinical laboratory setting, and the advancement of novel molecular microbiology diagnostic methods for the detection of human pathogens.
Selected Publications
- Tomita T, Mukhopadhyay D, Han B, Yakubu R, Tu V, Mayoral J, Sugi T, Ma Y, Saeij JPJ, Weiss LM. Toxoplasma gondii matrix antigen 1 is a secreted immunomodulatory effector. mBio. 2021 May 18;12(3):e00603-21.
- Tu V, Mayoral J, Yakubu RR, Tomita T, Sugi T, Han B, Williams T, Ma Y, Weiss LM. MAG2, a Toxoplasma gondii Bradyzoite Stage-Specific Cyst Matrix Protein. mSphere. 2020 Feb 19;5(1):e00100-20.
- Yakubu RR, Weiss LM, Silmon de Monerri NC. Post-translational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies. Mol Microbiol. 2018 Jan;107(1):1-23
- Yakubu, R. R., Silmon de Monerri, N. C., Nieves, E., Kim, K., & Weiss, L. M. Comparative Monomethylarginine Proteomics Suggests that Protein Arginine Methyltransferase 1 (PRMT1) is a Significant Contributor to Arginine Monomethylation in Toxoplasma gondii. Mol Cell Proteomics. 2017 Apr;16(4):567-580
- Tomita T, Sugi T, Yakubu R, Tu V, Ma Y, Weiss LM. Making home sweet and sturdy: Toxoplasma gondii ppGalNAc-Ts glycosylate in hierarchical order and confer cyst wall rigidity. mBio, 2017 Jan 10; 8:e02048-16
- Silmon de Monerri, N. C., Yakubu, R. R., Chen, A. L., Bradley, P. J., Nieves, E., Weiss, L. M., & Kim, K. The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions. Cell Host & Microbe, 2015 Nov 11;18(5), p.621-633
Awards
Laurence J. Marton Award for Excellence in Research