Rachael P. Jackman, PhD

Rachael P. Jackman, PhD

Adjunct Assistant Professor
Laboratory Medicine
Vitalant Research Institute

Vitalant Research Institute
270 Masonic Avenue
San Francisco, CA 94118
United States

Other UCSF Organizational Association(s)

Assistant Investigator, Vitalant Research Institute

Research and Clinical Interests

Our long-term research goals are to improve our understanding of the wide range of immune consequences to transfusion and other allogeneic exposures and to identify methods to modulate these responses to protect against alloimmunization and rejection. Through the use of our novel transfusion mouse models alongside clinical samples from a range of alloexposure patients, our goal is to identify the mechanisms involved in regulating the alloresponse, evaluate protective approaches, and determine how these responses may vary in different types of patients.

Selected Publications
  • Jackman, R.P., Utter, G.H., Muench, M.O., Heitman, J.H., Munz, M.M., Jackman, R.W., Biswas, H., Rivers, R.M., Tobler, L.H., Busch, M.P., Norris, P.J. (2012). “Distinct roles of trauma and transfusion in induction of immune dysregulation post-injury.” Transfusion 52(12): 2533-50. PMC3392528.
  • Jackman, R.P., Muench, M.O., Heitman, J.H., Law, J.P., Inglis, H., Marschner S., Goodrich R.P., Norris P.J. (2013). “Immune Modulation and Lack of Alloimmunization Following Transfusion with Pathogen Reduced Platelets in Mice.” Transfusion 53(11):2697-2709
  • Jackman, R.P., Deng, X., Bolgiano, D., Lebedeva, M., Heitman, J.W., Busch, M.P., Slichter, S., Norris P.J. (2013). “Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants.” Blood 121(16):3261-3266.
  • Jackman, R.P., Cruz, G.I., Nititham,, J., Triulzi, D.J., Barcellos, L.F., Criswell, L.A., Norris, P.J., Busch, M.P. (2018). “Increased Allo and Auto Reactive Anti-Human Leukocyte Antigen Antibodies Associated With Systemic Lupus Erythematosus and Rheumatoid Arthritis.” Lupus Science & Medicine, 5(1):e000278.
  • Tran, J.Q., Muench, M.O., Heitman, J.W., Jackman, R.P. (2019). “Allogeneic major histocompatibility complex antigens are necessary and sufficient for partial tolerance induced by transfusion of pathogen reduced platelets in mice.” Vox Sanguinis, In Press.
Additional Information