Nancy M. Joseph, MD, PhD

Nancy M. Joseph, MD, PhD

Associate Professor
Surgical Pathology
Specialty Areas
Surgical Pathology
Gastrointestinal Pathology
Molecular Pathology
Gynecologic Pathology
Thoracic Pathology

Pathology, Box 0102
513 Parnassus Avenue, Room HSW-450
San Francisco, CA 94143
United States

Hospital Affiliations
UCSF Parnassus Heights
UCSF Mount Zion
San Francisco VA Health Care System
Zuckerberg San Francisco General Hospital
Research and Clinical Interests

My clinical and research interests are in the areas of gastrointestinal and molecular pathology with a focus on improving tumor diagnosis and classification by integrating molecular data with histologic features and immunohistochemical data.

Selected Publications
  • Krings G*, Joseph NM*, Bean G, Solomon, D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, Van Zante M, Zaloudek C, Shin S, and Chen YY. Genomic Profiling of Breast Secretory Carcinomas Reveals Distinct Genetics from Other Breast Cancers and Similarity to Mammary Analogue Secretory Carcinomas. Modern Pathol. In press.
  • Bean GR, Joseph NM, Gill RM, Folpe AL, Horvai AE, Umetsu SE. Recurrent GNAQ mutations in anastamosing hemangiomas. Modern Pathol. 2017 May;30(5):722-727. doi: 10.1038/modpathol.2016.234.
  • Joseph NM, Pineda C, and Rabban JT. DNA Genotyping of Non-Molar Donor Egg Pregnancies with Abnormal Villous Morphology: Allele Zygosity Patterns Prevent Misinterpretation as Complete Hydatidiform Mole. Int J Gynecol Pathol. 2017 Apr 29. doi: 10.1097/PGP.0000000000000395. [Epub ahead of print]
  • Joseph NM, Chen YY, Nasr A, Yeh I, Talevich E, Onodera C, Bastian BC, Rabban JT, Garg K, Zaloudek C, and Solomon D. Genomic Profiling of Malignant Peritoneal Mesothelioma Reveals Recurrent Alterations in Epigenetic Regulatory Genes BAP1, SETD2, and DDX3X. Modern Pathol. 2016 Nov 4. doi: 10.1038/modpathol.2016.188.
  • Kline CN*, Joseph NM*, Grenert JP, Van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Campomanes A, Banerjee Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn M, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T,†, and Solomon T,† Targeted next-generation sequencing of pediatric brain tumor patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy