Alexis J. Combes, PhD

Alexis J. Combes, PhD

Assistant Professor
Specialty Areas
System Immunology

Pathology, Box 0511
513 Parnassus Avenue, Room S-816
San Francisco, CA 94143
United States

Hospital Affiliations
UCSF Parnassus Heights
Other UCSF Organizational Association(s)

Faculty Member, Bakar ImmunoX initiative
Faculty Member, The Benioff Center for Microbiome Medicine, UCSF, San Francisco, CA
Director, Disease-to-biology CoLab, EVCP 
Biomedical Sciences (BMS) Program

Research and Clinical Interests
  • Combes AJ, Samad B, … Krummel MF#. Discovering dominant tumor immune archetypes in a pan-cancer census. Cell. 2022
  • Combes AJ, Samad B, Krummel MF. Defining and using immune archetypes to classify and treat cancer. Nat Rev Cancer. 2023
  • Mujal AM, Combes AJ,….Krummel MF. Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer. Cancer Immunol Res. 2022 
  • Vallvé-Juanico J..., Combes AJ, Giudice LC. Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood. BMC Med. 2022
  • Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, …, Krummel MF. Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 

2023: Stuart Lindsay Endowed Chair in Experimental Pathology

Additional Information