Pathology Research Programs
As a leader in academic pathology, our department has a long tradition of excellence in basic, translational and clinical research. The research activities of the Department interface closely with numerous research programs at UCSF, including those at the Comprehensive Cancer Center. Our research faculty are members of the two large graduate programs at UCSF: the Program in Biological Sciences and the Biomedical Sciences Program. Well over one hundred postdoctoral research fellows and graduate students are being trained in the laboratories in the Department.
In addition, investigators in the Department are involved in a large number of translational research projects on diverse topics, including: breast tumors; liver, kidney and gastrointestinal diseases; transplantation; lymphoid neoplasms. Information about the research activities of individual faculty members may be found in their biographical sketches.
Major Research Themes
Although our research activities span a wide range of interests, many of our large, independently funded research groups fall into the following major thematic areas:
Pathogens and Immunity
Abul K. Abbas, MBBS
autoimmunity, T cell biology
Alexis J. Combes, PhD
system immunology, oncology
Eric J. Huang, MD, PhD
brain innate immunity, neuroinflammation
Matthew K. Krummel, PhD
immune cell interactions, ImmunoX initiative
Cancer
Boris Bastian, MD
genetics and biology of melanoma
Robert Blelloch, MD, PhD
microRNAs, stem cells, and cancer
Alexis J. Combes, PhD
system immunology, oncology
Jayanta (Jay) Debnath, MD
cancer pathogenesis
Joanna Phillips, MD, PhD
glioblastoma and tumor microenvironment
Matthew D. Stachler, MD, PhD
Barrett's esophagus
Thea Tlsty, PhD
cancer progression, genomic instability
Neuropathology
Eric J. Huang, MD, PhD
neural development, neurodegeneration
Amber L. Nolan, MD, PhD
traumatic brain injury, neural circuit dysfunction
Joanna J. Phillips, MD, PhD
brain tumor microenvironment
David Solomon, MD, PhD
molecular genetics of brain tumors
Inflammation and Tissue Injury
Walter Finkbeiner, MD, PhD
lung pathology
Zoltan G. Laszik, MD, PhD
gene expression, tissue inflammation, kidney diseases
Aras N. Mattis, MD, PhD
liver diseases
Stephen L. Nishimura, MD
integrins
Carolyn Sangokoya, MD, PhD
RNA biology, iron pathobiology, stem cells, liver disease, regenerative medicine