Nandan Padmanabha, MBBS

Assistant Professor

Laboratory Medicine

Division

Hematopathology

Specialty Areas

Myeloid and Lymphoid Neoplasms

[email protected]

185 Berry St
Suite 2113
San Francisco, CA 94107
United States

Hospital Affiliations

UCSF Parnassus Heights

UCSF Mission Bay

UCSF Mount Zion

Zuckerberg San Francisco General Hospital

Research and Clinical Interests

Clinical Interests: Diagnosis of leukemias, lymphomas, myelodysplastic syndromes, myeloproliferative neoplasms, and plasma cell neoplasms from bone marrow, lymph node, and other tissue biopsies. Particular interest in lymphomas relapses after CAR T-cell therapy. Research Interests: I study how lymphomas and other hematologic neoplasms change after CAR T-cell therapy, including why some large B-cell lymphomas do not respond to treatment. I also work on how specific mutations and translocations relate to morphology and classification in myeloid and plasma cell neoplasms, including IGH::CCND3 myeloma and cohesin-mutated myeloid neoplasms. A third area is the use of digital image analysis and AI to make quantitative tasks in hematopathology more reproducible across pathologists and institutions.

Selected Publications

Padmanabha N, Sperling AS, Morgan EA, Michaels PD, Sadigh S. Clinicopathologic characterization of plasma cell neoplasms with IGH::CCND3. Am J Clin Pathol. 2026 Jul 6;166(1):aqag080. PMID: 42418658.

Padmanabha N, Oganesyan R, O’Brien L, Li D, Widener S, Hakamy B, Yilmaz O, Collins LC, Deshpande V, Gonzalez RS, Vyas M. Digital Ki-67 quantification in neuroendocrine tumours: comparing performance of camera-captured images and open-source platforms across imaging modalities. Journal of Clinical Pathology. 2026 May 25:jcp-2026-210759. doi: 10.1136/jcp-2026-210759. Epub ahead of print. PMID: 42185043.

Oganesyan R, Yilmaz O, Chornenkyy Y, Kantekure K, Ono Y, Hakamy B, Padmanabha N, Deshpande V, Gonzalez RS, Vyas M. Defining hotspot for estimation of Ki-67 proliferation index of neuroendocrine tumors: QuPath algorithm vs. manual assessment. Journal of Pathology Informatics. 2026 Mar 24;21:100655. PMID: 42057919.

Vyas M, Bellizzi AM, McHugh K, Allende D, Shi C, Ma C, Shroff S, Cox BK, Singhi A, Padmanabha N, Gonzalez RS. Extrapancreatic Gastrointestinal Tract Grade 3 Well-Differentiated Neuroendocrine Tumors Behave Aggressively Compared With Lower-Grade Tumors Despite Similar Morphology. American Journal of Surgical Pathology. 2026 May 1;50(5):524-534. Epub 2026 Feb 20. PMID: 41717808.

Fu R, Boulougoura A, Yu S, Li H, Pan W, Endo Y, Bhargava R, Satyam A, Kasinath V, Jordan J, Padmanabha N, Tsokos MG, Abdi R, Tsokos GC. Podocyte Interleukin-23 Receptor Signaling in the Pathogenesis of Lupus Nephritis. Arthritis and Rheumatology. 2026 Mar;78(3):672-683. Epub 2025 Dec 30. PMID: 40948101.

Padmanabha N, Chornenkyy Y, Pan W, Vyas M, Yilmaz O. Lymph node threshold in colorectal cancer: surgeons' perspectives and practices. Journal of Clinical Pathology. 2025 Sep 18;78(10):673-677. PMID: 40730454.

Lee SH, Yilmaz O, Padmanabha N, Deshpande V, Yilmaz O. Assessing venous invasion in stage II colon cancer: optimal elastin stains and survival analysis. Journal of Clinical Pathology. 2025 Jul 18;78(8):527-534. PMID: 38849196.

Padmanabha N, Weinstock MJ, Xu S, Lepe M, Garrett LA, Kappes UP, Michaels PD. Transdifferentiation of Diffuse Large B-cell Lymphoma to a Poorly Differentiated Neoplasm Following CAR T-cell Therapy. Journal of Hematopathology. 2024 Jun 15. PMID: 38878262.

Hirt CK, Padmanabha N*, Michaels PD. Cohesin Complex Mutations in Myeloid Neoplasms are Enriched for SRSF2, RUNX1, TET2, and NRAS Co-mutations and Morphologic Dysplasia. Leukemia Research. 2023 Sep;132:107357. PMID: 37481994.

Sachdeva H, Nirupama M, Padmanabha N, Sreeram S, Lobo FD, Pai R, Sreedharan S. Histopathological Study of Benign Tumours of the Larynx: A Descriptive Study in Coastal Karnataka. Indian Journal of Otolaryngology and Head Neck Surgery. 2022 Oct;74(Suppl 2):2019-2023. PMID:36452659.

Ghosh A, Nirupama M, Padmanabha N, Kini H. Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation. Iranian Journal of Pathology, 2020; 15(4): 268-273. PMID: 32944038.

Padmanabha N, Kini JR, Alwani, AA, Sardesai A. Acceptability of Human Papillomavirus Vaccination Among Medical Students in Mangalore, India. Vaccine 2019;37(9):1174-1181. PMID: 30709724.

Nandan P, Nayanatara AK, Poojary R, Bhagyalakshmi K, Nirupama M and Kini RD. Protective role of Coadministration of Vitamin D in Monosodium Glutamate Induced Obesity in Female Rats. Journal of National Medical Association 2018;110(1): 98–102. PMID: 29510852.

Joseph N, Srinath R, Ramanathan A, Gupta AK, Nandan P, Afnan R. Awareness of Risk Factors, Warning Signs, and Immediate Management Measures of Noncommunicable Diseases: A Multihospital-Based Study. Journal of Natural Science, Biology and Medicine 2018;9:227-35. 9.

Padmanabha N, Muralimunglimane N, Kumar NA, Kodavanji B, Kini JR, Poojary R. Ameliorative Role of Vitamin D on Prenatal and Postnatal Exposure of Monosodium Glutamate Induced Steatohepatitis in Rat Pups. Pharmacognosy Journal 2018;10(2):371-375. Nandan P, Nirupama M, Kini JR, Gopal S, Sahu KK, Rai S. Profile of Pancreatic Tumors at a Tertiary Care Center. Indian Journal of Cancer 2016;53:296-9. PMID: 28071631.

Awards

Outgoing Resident Teaching Award	Beth Israel Deaconess Medical Center	2025
Best Trainee Abstract Award	Association of Indian Pathologists in North America	2024
Pathologist-in-Training Travel Award	USCAP Foundation	2022