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COMPLETE BLOOD COUNT (CP, CDP)

Item Value
Approval req'd? no
Available Stat? Yes
Test code CP, CDP
Performed by? Hematology
Sendout? no
Price range $
In House Availability 24 hours/ 7 days

Principle Automated flow cytometry-based system (ADVIA, Siemens) that uses light scatter and myeloperoxidase staining to provide a complete blood cell count and WBC differential. Hemoglobin is measured colorimetrically, using a cyanide-free method. Hematocrit (HCT), MCH and MCHC are calculated. A centrifuged microhematocrit, unlike the calculated HCT obtained by the ADVIA system, includes a small percentage of plasma trapped in the cell column. The actual degree of plasma trapping varies considerably and is highest with stiff red cells, as in iron deficiency and sickle cell anemia. The centrifuged microhematocrit may thus be several percentage points higher than the calculated HCT.
Container type EDTA (lavender top) tube
Amount to Collect 3 mL (minimum volume 1mL)
Sample type EDTA Whole blood
Special instructions CP includes a complete blood count; i.e., WBC, RBC, hemoglobin, hematocrit, RBC indices and platelet count. It does NOT include differential leukocyte count or RBC morphology.

CDP includes all parameters measured in a CP plus a differential leukocyte count (see also Differential Leukocyte Count, Automated).
Normal range PLT 150,000 – 400,000/mcL blood (adult and pediatrics).

Adults (18 years and older)
(Men) Conventional Units SI Units
WBC 3.9 - 11.7 x 103/mcL 3.9 - 11.7 x 109/L
RBC 4.40 - 5.90 x 106/mcL 4.4 - 5.9 x 1012/L
HGB 13.3 - 17.7 g/dL 133 - 177 g/L
HCT 39.8 - 52.2 % 0.40 - 0.52
MCV 80 - 100 fL 80 - 100 fL
MCH 26.6 - 33.8 pg 26.6 - 33.8 pg
MCHC 31.5 - 36.0 g/dL 315 - 360 g/L
PLT 150 - 400 x 103/mcL 150 - 400 x 109/L


Adults (18 years and older)
(Women) Conventional Units SI Units
WBC 4.0 - 11.6 x 103/mcL 4.0 - 11.6 x 109/L
RBC 3.80 - 5.20 x 106/mcL 3.80 - 5.20 x 1012/L
HGB 11.7 - 15.7 g/dL 117 - 157 g/L
HCT 34.9 - 46.9 % 0.35 - 0.47
MCV 80 - 100 fL 80 - 100 fL
MCH 26.4 - 34.0 pg 26.4 - 34.0 pg
MCHC 31.4 - 35.8 g/dL 314 - 358 g/L
PLT 150 - 400 x 103/mcL 150 - 400 x 109/L

TABLE H-I. REFERENCE RANGE (RBC): PEDIATRICS (Conventional Units)


Age (106/mcL)
RBC
(g/dL)
HGB
(%)
HCT
(fL)
MCV
(pg)
MCH
(g/dL)
MCHC
<1 day 3.90-5.50 13.5-19.5 42.0-60.0 98-118 31.0-37.0 30.0-36.0
1-7 days 3.90-6.60 13.5-22.5 42.0-67.0 88-126 28.0-40.0 28.0-38.0
8-14 days 3.60-6.30 12.5-21.5 39.0-66.0 86-126 28.0-40.0 28.0-38.0
15 days- <1 mo 3.00-6.20 10.0-20.5 31.0-66.0 85-124 28.0-40.0 29.0-38.0
1 mo- <2 mos 2.70-5.40 9.0-18.0 28.0-55.0 77-123 26.0-40.0 29.0-37.0
2- <3 mos 2.70-4.90 9.0-13.5 28.0-42.0 74-115 25.0-35.0 29.0 37.0
3- <6 mos 3.10-4.50 9.5-13.5 29.0-41.0 74-108 25.0-35.0 30.0-36.0
6 mos- <2 yrs 3.70-5.30 10.5-13.5 33.0-39.0 70-86 23.0-31.0 30.0-36.0
2- <6 yrs 3.90-5.30 11.5-13.5 34.0-40.0 75-87 24.0-30.0 31.0-37.0
6- <12 yrs 4.00-5.20 11.5-15.5 35.0-45.0 77-95 25.0-33.0 31.0-37.0


12- <18 yrs:
Female 4.10-5.10 12.0-16.0 36.0-46.0 78-102 25.0-35.0 31.0-37.0
Male 4.50-5.30 13.0-16.0 37.0-49.0 78-98 25.0-35.0 31.0-37.0


Modified from: Dallman, P.R.: In Pediatrics, 16th ed. Rudolph, A., [ Editor ], New York, Appleton Century Crofts, Inc., 1977:1111. Nathan D.G., Orkin S.H.: Nathan and Oski's Hematology of Infancy and Childhood, 5th ed., Philadelphia, WB Saunders Co., 1998.

TABLE H-II. REFERENCE RANGE (RBC): PEDIATRICS (SI Units)
Age (1012/L)
RBC
(g/L)
HGB
(%)
HCT
(fL)
MCV
(pg)
MCH
(g/L)
MCHC
<1 day 3.90-5.50 135-195 0.42-0.60 98-118 31.0-37.0 300-360
1-7 days 3.90-6.60 135-225 0.42-0.67 88-126 28.0-40.0 280-380
8-14 days 3.60-6.30 125-215 0.39-0.66 86-126 28.0-40.0 280-380
15 days- <1 mo 3.00-6.20 100-205 0.31-0.66 85-124 28.0-40.0 290-380
1 mo- <2 mos 2.70-5.40 90-180 0.28-0.55 77-123 26.0-40.0 290-370
2- <3 mos 2.70-4.90 90-135 0.28-0.42 74-115 25.0-35.0 300-360
3- <6 mos 3.10-4.50 95-135 0.29-0.41 74-108 25.0-35.0 300-360
6 mos- <2 yrs 3.70-5.30 105-135 0.33-0.39 70-86 23.0-31.0 300-360
2- <6 yrs 3.90-5.30 115-135 0.34-0.40 75-87 24.0-30.0 310-370
6- <12 yrs 4.00-5.20 115-155 0.35-0.45 77-95 25.0-33.0 310-370


12- <18 yrs
Female: 4.10-5.10 120-160 0.36-0.46 78-102 25.0-35.0 310-370
Male: 4.50-5.30 130-160 0.37-0.49 78-98 25.0-35.0 310-370


Modified from: Dallman, P.R.: In Pediatrics, 16th ed. Rudolph, A., [Editor], New York, Appleton Century Crofts, Inc., 1977:1111. Nathan D.G., Orkin S.H.: Nathan and Oski's Hematology of Infancy and Childhood, 5th ed., Philadelphia, WB Saunders Co., 1998.
Synonyms CBC;
Additional information INDICATIONS: Numerous, including initial screening, diagnosis, and monitoring the course of the illness.
References 1. Gottfried, E.L.: Erythrocyte Indexes with Electronic Counter. N Engl J Med. 300:1277, 1979.

2. Samiy, A.H.: Textbook of Diagnostic Medicine, Philadelphia, Lea & Febiger, 1987:845 –858

3. Buttanello, M.: Automated Blood Cell Counts,Am.J.Clin.Path. 130(1):104-116, 2008
CPT coding 85027, 85025

Last Updated 7/9/2014 6:06:51 PM
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