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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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COMPLEMENT C3, SERUM, SYNOVIAL FLUID AND COMPLEMENT C4, SERUM

Item Value
Available Stat? No
Test code C3 or C4
Performed by? Chemistry
Sendout? no
Price range $$$
In House Availability Once a week (M, Th = processing day)
Principle Rate Immunonephelometry.
Interpretation Rate Immunonephelometry.
Collection Instructions For the interpretation of the complement activity in joint fluid, a simultaneous measurement of serum complement must be made.
Normal range C3: 86-184 mg/dL (0.86-1.849 g/L)
C4: 20-59 mg/dL (0.20-0.59 g/L)
Stability 24 hours at 2-8°C, 2 weeks at -20°C
Additional information INDICATIONS: Evaluation of autoimmune disease activity.
References 1. Beckman Immage Chemistry Information Manual 962248 February 1997. Beckman Coulter, Inc. Fullerton, CA.

2. Ritzman: Serum Protein Abnormalities. Little Brown & Co., 1975.

3. Wagner, E. Complement and Kinins: Mediators of Inflammation, in Clinical Diagnosis and Management by Laboratory Methods, 20th ed. JB Henry, ed. WB Saunders Co., NY, pp 892-913, 2001.
CPT coding 86361
Last Updated 10/16/2012 7:31:49 PM
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