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Lab Manual for UCSF Clinical Laboratories

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CALCIUM, URINE

Item Value
Available Stat? Yes
Test code CAU
Performed by? Chemistry
Sendout? no
Price range $
In House Availability 7 days
Principle Analysis is based on the reaction of calcium with an indicator dye (o-cresolphthalein complexone) to form a colored complex.
Interpretation 1. Urine increased: hyperparathyroidism, idiopathic hypercalciuria, high calcium diet, immobilization, bone lysis of any etiology, drugs (mercurial diuretics, ammonium chloride), Fanconi's syndrome, renal tubular acidosis.

2. Urine decreased: hypoparathyroidism, rickets, osteomalacia, steatorrhea, renal failure, metastatic prostate cancer.
Collection Instructions Refrigerate urine during collection or preserve with 15 mL 6N HCl during collection if only calcium is requested, otherwise the laboratory will acidify an aliquot.
Normal range

Urine 50 – 300 mg/24 hr (varies with diet)
12.5 – 74.9 mmol/24 hr


Interferences Many drugs can increase or decrease urine calcium.

1. Decrease: aging, standing of sample.

2. Increase: bed rest, same as serum.

If you have a question, please contact the Laboratory Medicine Resident in Clinical Chemistry (x65527, or pager (415) 443-2311).
References Bayer(TM) Clinical Methods Calcium (39) B01-4145-01 Advia 1650 Operator's Guide. PN 073-5001-09. Last accessed June 2003. Siemens Medical Solutions Diagnostics, Malvern, PA.
Last Updated 6/18/2011 8:09:42 AM
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