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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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FENTANYL, URINE

Item Value
Available Stat? Yes
Test code FENT
Performed by? Chemistry
Sendout? no
Price range $
In House Availability Stat or routine, 24 hours/7 days
Principle Competitive enzyme immunoassay
Interpretation CLINICAL SIGNIFICANCE: Fentanyl is a synthetic opioid analgesic prescribed for pain and/or anesthesia. Fentanyl is extensively metabolized by N-dealkylation and hydroxylation. More than 90% of the dose is eliminated as norfentanyl and hydroxylated metabolites. Less than 7% of the dose is excreted unchanged in the urine.

This immunoassay does not detect fentanyl metabolites, such as norfentanyl. As a result, the sensitivity of this assay for detecting fentanyl use is 96%. Fentanyl false negatives are possible. This assay is not sensitive to the other opioids, such as codeine, morphine, hydrocodone, hydromorphone, oxycodone or oxymorphone.

This assay does detect the designer drug, acetyl fentanyl.

CUTOFF: 2 ng/mL

Drug Detection Period (approximate guideline) = 1 – 3 days

Positive results are not confirmed. Confirmation can be performed as an "add on" test by special request if the specimen is available. Page the Chemistry/Toxicology Fellow on call at 719-5166 if you have questions about confirmation testing.

Container type sterile, screw-capped container, without preservative
Amount to Collect 15 mL
Sample type Urine
Normal range Negative
Stability Minimum 1 week at 2 - 8
Turn around times Screening results are reported within 1 to 8 hours
Last Updated 9/12/2013 9:04:40 AM
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