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PROTEIN, URINE

Item Value
Available Stat? No
Test code PROU
Performed by? Chemistry
Sendout? no
Price range $$
In House Availability 7 days
Principle Pyrogallol red dye reacts with proteins in urine to form a colored complex. Absorbance of the complex is proportional to the protein concentration in the sample
Interpretation Any result greater than 0.15 g/24 hr (0.15 g/d) is abnormal and suggests glomerular damage or other forms of renal disease. Minimal proteinuria (< 0.5 g/d) is seen in chronic pyelonephritis, polycystic kidney, renal tubule disease, moderate proteinuria (0.5 - 4.0 g/d), pre-eclampsia. Heavy proteinuria (> 4 g/d) is seen in nephrotic syndrome, but also acute and chronic glomerulonephritis, lupus nephritis, amyloidosis, renal venous congestion. Non-symptomatic orthostatic proteinuria may produce 1 g/d.

Very dilute urine samples (specific gravity ≤ 1.010) may yield artificially high 24 hour protein concentrations in large volume (> 2500 mL) samples.
Normal range < 0.16 g/24 hr
Stability Urine stable for 24 hours at 2-8°C.
References 1. Randox Total Protein (Urine) Product Insert. UP 1570. Rev. 17/05/02. Randox Laboratories Ltd. Ardmore, United Kingdom.

2. Manuel, Y., Revillard, J.P., and Betuel, H., (eds): Proteins in Normal and Pathological Urine, Basel, S. Karger, 1970.
CPT coding 84156
Last Updated 10/23/2012 4:34:41 PM
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