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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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LIPASE

Item Value
Available Stat? Yes
Test code LIPA
Performed by? Chemistry
Sendout? no
Price range $$
In House Availability Routine: 7 days;
STAT: 24 hours/ 7 days
Principle A synthetic, chromogenic substrate is cleaved by lipase. The lipase activity in the specimen is proportional to the change in absorbance of the free chromogen. The reagents contain colipase.
Interpretation Lipase increases rapidly in patients with acute and recurrent pancreatitis, pancreatic abscess, or pseudocyst, pancreatic trauma, pancreatic cancer, common bile duct obstruction, and ingestion of drugs that are toxic to the pancreas. It is also increased by most inflammatory conditions in the abdominal cavity, biliary tract disease, abdominal abscesses, and renal failure. Lipase is more specific than total amylase in the diagnosis of acute pancreatitis. As such, in-house testing for amylase has been discontinued at SFGH.
Container type gel tube (gold or green top)
Amount to Collect 2 mL
Sample type Blood
Normal range Plasma and Serum, 7 – 58 U/L
Stability Serum stable 3 weeks at 4°C.
References 1. Tietz NW (ed). Fundamentals of Clinical Chemistry. Ed. 5. Philadelphia: WB Saunders, 377-378, 2001.

2. Young DS. Effects of Drugs on Clinical Laboratory Tests. Ed. 4. Washington, DC, AACC Press, 1995.

3. Lipase Colorimetric, rev. 28/02/02 wpt. Randox Laboratories Ltd. Crumlin, UK
CPT coding 83690
Last Updated 11/12/2008 11:24:35 AM
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