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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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HAPTOGLOBIN

Item Value
Available Stat? No
Test code HAPT
Performed by? Chemistry
Sendout? no
Price range $$$
In House Availability Twice a week
Principle Rate immunonephelometry.

Interpretation 1. Increase: Haptoglobin is an acute phase reactant which increases during acute and chronic inflammation and neoplasms (Hodgkin's disease burns).

2. Decrease: Very low values occur in pernicious anemia, hemolytic anemia, and blood transfusion reactions, as well as severe in liver disease (haptoglobin is synthesized by the liver) lupoid hepatitis and paroxysmal nocturnal hemoglobinuria. Occasional patients have a congenital absence of haptoglobin (4% of African-Americans).
Container type gold top gel tube
Amount to Collect 1 mL
Collection Instructions plasma samples not acceptable. Hemolyzed specimens will not be assayed.
Sample type Blood
Special instructions For suspected transfusion reactions send a pre-transfusion specimen and another specimen 8 to 24 hours after the suspected transfusion reaction.
Normal range 31 - 246 mg/dL (0.31 - 2.46 g/L), IFCC
Stability 72 hrs at 4°C.
Additional information INDICATIONS: To rule out hemolysis. Mandatory in work-up of blood transfusion reaction.

References 1. Ritzman, S. ed.: Serum Protein Abnormalities, Little Brown & Co. 1975, pp 219-229.

2. Henry, J.B., ed: Clinical Diagnosis and Management by Laboratory Methods, 20th Ed. W.B. Saunders, Philadelphia, PA, 2001, pp 256-257.

3. Beckman Immage Chemistry Information Manual 962248 February 1997. Beckman Coulter, Inc. Fullerton, CA.
CPT coding 83010
Last Updated 10/20/2012 10:05:10 AM
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