Our Research Focus
In most neurologic diseases, the pathologic process does not involve the entire brain. Instead, only specific subsets of neurons or glial cells are injured or die, and the nature of this selective brain injury determines the symptoms and clinical course of each disease. The aim of our lab is to uncover the molecular basis of this selective vulnerability. To accomplish this, we are currently focusing on (1) the role of intrinsic antioxidant defenses in the regulation of neuronal survival and in the modulation of neuronal signaling and (2) the role of microRNAs in synaptic plasticity and malplasticity.
