Item Value
Test name Busulfan Pharmacokinetics, Pediatric (Non-Research)
Available Stat? No
Turn around times Results available same day by 1300 hours
In House Availability Run Monday-Friday AM with prior notice (excluding holidays)
Performed by China Basin Chemistry
Normal range
Container type Dark green top on ice drawn at specific times
Amount to Collect 2 mL blood for each sample
Collection Instructions Samples should only be collected Sunday through Friday and the collection MUST be completed and the last sample delivered to the laboratory by 5:00AM in order to provide results the same day.

Testing should be ordered in APeX.

For PK studies on the first busulfan dose, the first sample should be drawn immediately after termination of the IV infusion. For PK studies on the steady state busulfan doses, the first sample should be drawn immediately before the start of the IV infusion. The remaining samples should be drawn at the times listed on the busulfan PK sheets (use correct PK sheet for each study: e.g. Q6hr, Q12hr or Q24hr).

Each patient sample should have a label affixed to it, and the EXACT time of collection should be written on the label or the APeX requisition and on the busulfan PK sheet. Hand-carry the sample to lab on ice with the requisition. Make sure to notify lab staff that you are delivering a busulfan sample, DO NOT simply leave it at the desk. Busulfan is unstable therefore EACH sample must be transported on ice to the laboratory immediately after collection for processing and freezing. With the final sample, bring the busulfan PK sheet with the correct collect times completed for each sample to the lab.

Click here for busulfan PK sheet, Q6hr
Click here for busulfan PK sheet, initial dose, Q12hr
Click here for busulfan PK sheet, steady state dose, Q12hr
Click here for busulfan PK sheet, initial dose, Q24hr
Click here for busulfan PK sheet, steady state dose, Q24hr
Click here for busulfan PK sheet, gene therapy
Sample type Heparinized plasma

If you have additional questions regarding this test, please call: 415-353-1667