Item Value
Test name Paraneoplastic Antibody Evaluation, Serum
Available Stat? No
Turn around times 3-4 weeks
Performed by Mayo
Normal range
Antibody Titer
Antineuronal Nuclear Antibody-Type 1 (ANNA-1) <1:240

Antineuronal Nuclear Antibody -Type 2 (ANNA-2) <1:240
Antineuronal Nuclear Antibody -Type 3 (ANNA-3) <1:240
Anti-Glial/Neuronal Nuclear Antibody-Type 1 (AGNA-1) <1:240
Purkinje Cell Cytoplasmic Antibody, Type 1 (PCA-1) <1:240
Purkinje Cell Cytoplasmic Antibody, Type 2 (PCA-2) <1:240
Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr) <1:240
Amphiphysin Antibody <1:240
CRMP-5-IgG <1:240*
Striational (Striated Muscle) Antibodies <1:60
N-Type Calcium Channel Antibody ≤ 0.03 nmol/L
P/Q-Type Calcium Channel Antibody ≤ 0.02 nmol/L
ACh Receptor (Muscle) Binding Antibody ≤ 0.02 nmol/L
AChR Ganglionic Neuronal Antibody ≤ 0.02 nmol/L
Neuronal VGKC Autoantibody ≤ 0.02 nmol/L


*Note: Titers lower than 1:240 are detectable by recombinant CRMP-5 Western blot analysis. CRMP-5 Western blot analysis will be done on request on stored serum (held 4 weeks). This supplemental testing is recommended in cases of chorea, vision loss, cranial neuropathy, and myelopathy. Call the Neuroimmunology Laboratory at 800-533-1710 or 507-266-5700 to request CRMP-5 Western blot.

Neuron-restricted patterns of IgG staining that do not fulfill criteria for amphiphysin, ANNA-1, ANNA-2, ANNA-3, AGNA-1, PCA-1, PCA-2, PCA-Tr, or CRMP-5-IgG may be reported as "unclassified antineuronal IgG." Complex patterns that include non-neuronal elements may be reported as "uninterpretable."
Container type Red top, Gold top
Amount to Collect 6 mL blood
Sample type Serum

If you have additional questions regarding this test, please call: 415-353-1667