Item Value
Test name KRAS Mutation testing
Available Stat? No
Turn around times 7-10 days
In House Availability Test performed once a week, with DNA extraction set up on Mondays and Wednesdays, test run on Tuesday or Wednesday, day shift only
Performed by Clinical Cancer Genomics Laboratory (CCGL)
Normal range Negative for KRAS mutations at codons 12 and 13.
Container type
Collection Instructions Blocks selected for KRAS mutation testing must contain tumor tissue. Areas of tumor must contain at least 50% tumor cells. The lab can remove adjacent non-tumor tissue, so the entire slide does not need 50% tumor cells, just the area with tumor. Contact the laboratory (415-514-1035, AGCLab@ucsf.edu) if the specimen suitability is uncertain. Label slides with pathology case number and block identification.

Complete an Clinical Cancer Genomics Laboratory (CCGL) requisition and submit it with samples.

Click here for requisition form
Sample type Formalin-fixed, paraffin-embedded tissue. Tissue block or unstained slides. If sending unstained slides, we require five (5) 10-micron tissue sections on uncharged glass slides. One adjacent H&E stained slide should be included. Cytology smears may also be used for testing if there is sufficient tumor present. Contact the laboratory (415-502-3252) if testing on a cytology smear or other sample types is desired.

If you have additional questions regarding this test, please call: 415-353-1667