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Syphilis Screening for High Risk OB Only

Item Value
Available Stat? No
Test code PNRPR
Test group Syphilis
Performed by Immunology
In House Availability 3X per week, day shift
Method Flocculation
Collection Instructions Avoid hemolysis, transport to laboratory as soon as possible. If transport is delayed refrigerate the sample.
Container type Gold top
Amount to Collect 1.0 mL
Sample type Serum
Preferred volume 0.5 mL
Min. Volume 0.5 mL
UCSF Rejection Criteria Grossly lipemic, grossly hemolysed or contaminated samples
Normal range Non-Reactive
Synonyms Prenatal Infection
Stability Refrigerated 4 days
Turn around times 1-4 days
Reflex? Yes. If positive, titer and Treponemal Ab will be performed at additional charge.
Additional information This test is ONLY for high-risk OB patients who have not been previously screened for syphilis with imminent delivery expected. Orders from any other service will require approval by a Laboratory Medicine resident or attending. RPR is a manually performed test requiring significant time and effort from laboratory staff. General screening for syphilis should be performed using the Treponemal Antibody Screen (test code TREP). Monitoring therapy in patients with known syphilis should be performed using Non-treponemal (RPR) for Monitoring (test code RPRF).

RPR is a non-treponemal syphilis test using a cardiolipin substrate. Positive results will automatically be tittered and reflexed to the Treponemal Antibody Screen (PNTREP) at additional charge. Positive results on both tests provide strong evidence of syphilis. However, false positive tests can be seen in association with autoimmune disease, and cross-reactivity occurs with non-syphilis treponemal infections.

Last Updated 5/26/2017 4:25:29 PM
Entry Number 1784
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