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Autoimmune Encephalopathy panel, CSF

Item Value
Available Stat? No
Test code ENCEC
Performed by Mayo
Sendout? Yes
Method IFA/RIA/CBA/WB
Container type CSF tube or sterile collection tube
Amount to Collect 4 mL
Sample type CSF
Preferred volume 4 mL
Min. Volume 2 mL
UCSF Rejection Criteria Grossly blood samples
Processing notes Aliquot and freeze sample. Send to CB frozen. Order Mayo test code ENCEC
Ref Lab Rejection Criteria Grossly blood samples
Normal range
Stability Room temperature 3 days, refrigerated or frozen 4 weeks
Reflex? The following tests may be reflexively added and biilled for based on screening results if appropriate:

Amphiphysin Western blot
CRMP-5 Western blot confirmation
Paraneoplastic autoantibody Western blot confirmation
NMO/AQP4-IgG CBA
AMPAR-Ab titer
GABAR-Ab titer
NMDAR-Ab titer
Additional information This antibody panel may be useful for evaluating new onset encephalopathy (noninfectious or metabolic) comprising confusional states, psychosis, delirium, memory loss, hallucinations, movement disorders, sensory or motor complaints, seizures, dyssomnias, ataxias, nausea, vomiting, inappropriate antidiuresis, coma, dysautonomias, or hypoventilation.

Testing includes testing for Ab's to:

Neuronal VGKC autoantibody
AGNA-1
Amphiphysin
ANNA-1
ANNA-2
ANNA-3
CRMP-5-IgG
PCA-1
PCA-2
PCA-Tr
AMPAR-Ab
GABAR-Ab
NMDAR-Ab
GAD65
CPT coding 83519-90 Neuronal VGKC autoantibody
86256-90 AGNA-1
86256-90 Amphiphysin
86256-90 ANNA-1
86256-90 ANNA-2
86256-90 ANNA-3
86256 -90CRMP-5-IgG
86256-90 PCA-1
86256-90 PCA-2
86256-90 PCA-Tr
86255-90 AMPAR-Ab
86255-90 GABAR-Ab
86255-90 NMDAR-Ab
86341-90 GAD65

84182-90 Amphiphysin Western blot (if appropriate)
84182-90 CRMP-5 Western blot confirmation (if appropriate)
84182-90 Paraneoplastic autoantibody Western blot confirmation (if appropriate)
86255-90 NMO/AQP4-IgG CBA (if appropriate)
86256-90 AMPAR-Ab titer (if appropriate)
86256-90 GABAR-Ab titer (if appropriate)
86256-90 NMDAR-Ab titer (if appropriate)
LOINC code 53714-2, 35142-9, 24400-4, 24401-2, 35144-5, 35385-4,14248-9, 35143-7, 51748-2, 53708-4
Last Updated 7/6/2015 8:35:32 AM
Entry Number 1634
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