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Clinical Question: Does my patient have acute porphyria?

Item Value
ID 7
Question Does my patient have acute porphyria?
AlgorithmLink Click here for algorithm
AlgorithmDescription Porphyric attacks may be induced by exposure to a variety of drugs, including barbiturates, chloral hydrate, diazepam, hydantoin, griseofulvin, and others or by hormonal changes, such as during puberty, menstruation, or pregnancy. Minor elevations of porphyrins (less than 2 to 3 times normal) may be due to an acute illness, liver disease, ethanol intake, estrogens, iron overload, hemodialysis, and exposure to heavy metals, pesticides, and herbicides. Care should be taken in specimen collection and handling since exposure to light or increased temperature leads to decreased levels of these metabolites.
ICD10 E80, E80.2
PubMedID

 

Tests associated with this clinical question:

Click on the test name for more information about the use of this test to answer this clinical question

ID Test Code Test Name Comment
32 PBQTR Miscellaneous Outside Laboratory Test Not specified
33 ALAQR Porphyrins, Fecal
Not specified
34 PORFUR Delta-Aminolevulinic Acid Quantitative, random urine Not Specified
35 MOLT (Order in Apex as 'Miscellaneous Outside Lab Test' using the complete test name above) Porphobilinogen, Quantitative, random urine Not Specified
36 MOLT Misc. Outside Laboratory Test Porphryins, Fractionated, plasma
37 UPGS Porphobilinogen deaminase, RBC Not Specified
38 ALAD Porphyrins, fractionated, random urine Not Specified

 

Clinical Algorithm:

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