The immune system functions dynamically and assembles synaptic circuits on-demand. Our lab uses real-time microscopy to study motility and signaling processes as immune cells survey their environment and communicate with one another. We also study the dynamics of communication to identify patterns of interactions that make the immune system a ‘system’. We are then seeking to perturb those patterns/circuits to determine how they work and for therapeutic benefit. Over the years our studies have generated real-time ‘movie’ datasets; these were often the first demonstration of key concepts in immunology and cell biology.




Note about QuickTime MoviePlayer: You will need this installed on your computer in order to view movie files. This program is native to most newer Macs when they are delivered to your door so you probably won't have to install this if you have a Mac. If you don't have a recent version of QuickTime MoviePlayer or have a PC computer and want to view QuickTime files now and in the future, you can download a copy for free at For some monitor resolutions, it may be necessary to choose 'Movie' and 'Fill Screen' in order to fit the movie completely within a single screen.