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Scott R. VandenBerg, MD, PhD

Research and Clinical Interests

My research is aimed at the invasive motility of reactive and neoplastic astrocytes. A focus is the coordinate interactions of chemokines and growth factors in regulating the “invasive and motile” tumor cell phenotypes, using monolayer and three-dimensional matrix culture systems.

My clinical interests focus on the diagnostic classification of CNS tumors using histopathologic, immunohistochemical and molecular morphologic techniques.

Selected Publications

  • Kanamori M., VandenBerg S.R., Bergers G., Berger MS, Pieper R.O. (2004) Integrin ß3 overexpression suppresses tumor growth in a human model of gliomagenesis: implications for the role of beta3 overexpression in glioblastoma multiforme. Cancer Res. 64:2751-2758.
  • Swerdlow R.H., Redpath G.T., Binder D.R., Davis J.N., VandenBerg S.R. (2006) Mitochondrial DNA depletion analysis by pseudogene ratioing. J Neurosci Methods 150:265-71.
  • Baia G.S., Slocum A.L., Hyer J.D., Misra A., VandenBerg S.R., Feuerstein B.G., Deen D.F., McDermott, M.W., Lal, A. (2006) A Genetic Strategy to Overcome the Senescence of Primary Meningioma Cell Cultures. J. Neuro-Oncol. 78:113-121.
  • Cadieux B., Ching T-T., VandenBerg S.R., Costello J.F. (2006) Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, MTHFR allele status and increased proliferation. Cancer Res. 66:8469-8476.
  • Jackson E.L., Garcia-Verdugo J.M., Gil-Perotin S., Roy M., Quinones-Hinojosa A., VandenBerg S., Alvarez-Buylla A. (2006) PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron 51:187-199.
Scott R. VandenBerg, MD, PhD
  • Professor of Pathology and Neurological Surgery
  • Pathology
  • Neuropathology

Specialty Area

CNS Tumors

Contact Information

  • 505 Parnassus Avenue, Room M-551
  • San Francisco, CA 94143-0511

Other UCSF Organizational Association(s)

Tissue Core Director

  • Brain Tumor Research Center

Hospital Affiliation(s)

  • Moffitt-Long

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