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Won-Tak Choi, MD, PhD

Research and Clinical Interests

(1) Flow cytometric measurement of nuclear DNA content abnormalities in Barrett's esophagus, inflammatory bowel disease, gastric dysplasia/adenomas, and other cancer types; (2) Prognostic significance of the CXC chemokine receptor 4 (CXCR4) overexpression in hepatocellular and gastrointestinal tumor progression and metastasis; and (3) liver transplant pathology, including impact of donor liver steatosis on post-transplantation outcomes.

Selected Publications

  • Choi WT, Cherian S, and Soma L. Significance of CD10 Positive Clonal B-Cell Populations Identified by Flow Cytometry in Histologically Benign Gastric Biopsies. Journal of Hematopathology. 2016. June; 9(2): 59-66.
  • Choi WT, Swanson PE, Grieco VS, Wang D, and Westerhoff M. The Outcomes of "Atypical" and "Suspicious" Bile Duct Brushings in the Identification of Pancreaticobiliary Tumors: Follow-Up Analysis of Surgical Resection Specimens. Diagnostic Cytopathology. 2015. Nov; 43(11): 885-91.
  • Choi WT, Rabinovitch PS, Wang D, and Westerhoff M. Outcome of "Indefinite for Dysplasia" in Inflammatory Bowel Disease: Correlation with DNA Flow Cytometry and Other Risk Factors of Colorectal Cancer. Human Pathology. 2015. July; 46(7): 939-947.
  • Choi WT, Emond MJ, Rabinovitch PS, Ahn J, Upton MP, and Westerhoff M. "Indefinite for Dysplasia" in Barrett's Esophagus: Inflammation and DNA Content Abnormality are Significant Predictors of Early Detection of Neoplasia. Clinical and Translational Gastroenterology. 2015. March; 6: e81.
  • Choi WT, Yang Y, Xu Y, and An J. Targeting Chemokine Receptor CXCR4 for Treatment of HIV-1 Infection, Tumor Progression, and Metastasis. Current Topics in Medicinal Chemistry. 2014. Aug; 14(13): 1574-1589.
  • Choi WT, Kumar KS, Madani N, Han X, Tian S, Dong CZ, Liu D, Duggineni S, Yuan J, Sodroski JG, Huang Z, and An J. A Novel Synthetic Bivalent Ligand to Probe Chemokine Receptor CXCR4 Dimerization and Inhibit HIV-1 Entry. Biochemistry. 2012. Sept; 51(36): 7078-7086.
  • Choi WT, Nedellec R, Coetzer M, Colin P, Lagane B, Offord RE, Hartley O, and Mosier DE. CCR5 Mutations Distinguish N-terminal Modifications of RANTES (CCL5) with Agonist Versus Antagonist Activity. The Journal of Virology. 2012. Sept; 86(18): 10218-10220.
  • Choi WT, Duggineni S, Xu Y, Huang Z, and An J. Drug Discovery Research Targeting the CXC Chemokine Receptor 4 (CXCR4). The Journal of Medicinal Chemistry. 2012. Feb; 55(3): 977-994.

Selected Awards

  • 2011 - Young Investigator Award, 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012)
  • 2008 - Teachers Ranked as Excellent by Their Students (in Human Anatomy), University of Illinois College of Medicine

Additional Information

Won-Tak Choi, MD, PhD
  • Assistant Professor
  • Pathology
  • Division: Anatomic Pathology

Specialty Areas

  • Liver and Gastrointestinal Pathology

Contact Information

Hospital Affiliation(s)

  • Moffitt-Long
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