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Sanjay Kakar, MD

Research and Clinical Interests

GGI/liver/pancreatic pathology. Methylation and MSI in colorectal polyps and cancer. Staging of GI and hepatobiliary cancers. Appendiceal neoplasms. Genetic changes in hepatic adenoma, HCC, fibrolamellar HCC, cholangiocarcinoma.

Selected Publications

  • Kakar S, Deng G, Sahai V, Matsuzaki K, Tanaka H, Miura S, Kim YS. Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability. Arch Pathol Lab Med. 2008;132(6):958-64.
  • Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Dachrut S, Yabes A, Jain D, Ferrell LD. Chromosomal changes in fibrolamellar carcinoma: correlation with clinicopathologic features and survival. Mod Pathol 2009;22(1):134-41.
  • Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Adeyi O, Jain D, Ferrell LD. Chromosomal abnormalities determined by comparative genomic hybridization are helpful in the diagnosis of atypical hepatocellular neoplasms. Histopathology 2009; 55(2):197-205.
  • Kakar S, Deng G, Cun L, Sahai V, Young YS. High frequency of chromosomal instability, aberrant methylation and BRAF mutations in signet ring carcinoma of the colorectum. Mod Pathol. 2012;25(7):1040-7.
  • Evason KJ, Grenert JP, Ferrell LD, Kakar S. Atypical hepatocellular adenoma-like neoplasms with β-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas. Hum Pathol. 44(5):750-8.
  • Gregor K, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S. Immunohistochemical pitfalls in the diagnosis of scirrhous hepatocellular carcinoma. Mod Pathol. 2013;26(6):782-91.
  • Hale G, Liu X, Hu J, Xu Z, Che L, Solomon D, Tsokos C, Shafizadeh N, Chen X, Gill R, Kakar S. Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma. Mod Pathol. 2016;29(11):1370-1380.
  • Wen KW, Hale G, Shafizadeh N, Hosseini M, Huang A, Kakar S. Appendiceal Goblet Cell Carcinoid: Common Errors in Staging and Clinical Interpretation with a Proposal for an Improved Terminology. Hum Pathol 2017 (in press).

Selected Awards

  • 2006: Teacher of the Year, UCSF Anatomic Pathology
  • 2012-2013: President, Gastrointestinal Pathology Society
  • 2013-now: Member and Lead Author of lower GI and hepatobiliary cancer protocols, Cancer Committee, College of American Pathologists
  • 2014-15: Member, AJCC panels for staging updates of lower GI and hepatobiliary cancers
  • 2016-now: Vice president, Hans Popper Hepatopathology Society

Additional Information

Sanjay Kakar, MD
  • Professor of Pathology, University of California, San Francisco
  • Director, GI-Hepatobiliary Pathology Fellowship Program
  • Chief, GI-Hepatobiliary Pathology Service
  • Pathology
  • Surgical Pathology

Specialty Area

Gastrointestinal, Liver and Pancreatic Pathology

Contact Information

Mailing/Shipping Address:

  • UCSF Liver/GI Service
  • Department of Pathology, Box 0102
  • 505 Parnassus Avenue, Room M545
  • San Francisco, CA 94143
  • Tel: 415-353-1633
  • Fax: 415-353-1200

Hospital Affiliation(s)

  • Moffitt-Long
  • Veterans Administration
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