• Department of Pathology
  • Pathology Staff
• Department of Laboratory Medicine
  • Laboratory Medicine Staff
• Affiliated Hospitals
  • Moffitt-Long
  • Mount Zion Medical Center
  • San Francisco Veterans Affairs Medical Center
  • San Francisco General
• Faculty
  • Pathology
  • Laboratory Medicine

Research and Clinical Interests

My mission within the Department of Pathology is twofold. My major focus is genitourinary pathology, where I closely interact with the urologic oncology group of the UCSF Comprehensive Cancer Center concerning clinical and basic science problems. A large number of research projects amenable to resident participation are available in this area. Specific areas include radiologic-pathologic correlation studies and imaging technology development (mainly focused on MRI/MRSI of the prostate and kidney), biomarker discovery efforts, clinical-pathologic correlation studies, and tumor model construction and characterization. I also perform general surgical pathology sign out duties. For additional information, please link to:

• http://cancer.ucsf.edu/people/...
• http://cancer.ucsf.edu/prostate_spore/...
• http://cancer.ucsf.edu/prostate_spore/...

Selected Publications

• E Blaveri, JP Simko, JE Korkola, JL Brewer, F Baehner, K Mehta, S DeVries, T Koppie, S Pejavar, P Carroll and F Waldman, “GENE EXPRESSION PATTERNS IDENTIFY BLADDER CANCER SUBTYPES AND PREDICT OUTCOME,” Clin Cancer Res 11(11): 4044-55 (2005).
• Paris P, Weinberg V, Simko J, Andaya A, Albo G, Rubin M, Carroll P, Collins C, “Preliminary Validation of Prostate Cancer Metastatic Risk Biomarkers,” Int. J. Biomarkers 20(3): 141-45 (2005).
• WA Ricke, K Ishii, EA Ricke, JP Simko, YZ Wang, SW Hayward, and FR Cunha, “Steroid Hormones Stimulate Human Prostate Cancer Progression and Metastasis,” Int J Cancer 118(9): 2123-31 (2006).
• Hom JJ, Coakley FV, Simko JP, Qayyum A, Lu Y, Schmitt L, Carroll PR, Kurhanewicz J, “Prostate Cancer: Endorectal MR Imaging and MR Spectroscopic Imaging--Distinction of True-Positive Results from Chance-detected Lesions,” Radiology 238(1): 192-9 (2006).
• Rini BI, Weinberg V, Dunlap S, Elchinoff A, Yu N, Bok R, Simko J, Small EJ, “Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma,” Cancer 106(3): 566-75 (2006).
• JP Simko, FM Waldman, “Molecular and Special Techniques,” in Immunomicroscopy: A Diagnostic Tool for the Surgical Pathologist, 3rd Edition, C. Taylor, R. Cote Eds. (Elsevier, St. Louis, 2006).

• Assistant Professor
• Pathology and Urology

Specialty Area

Prostate, bladder and kidney tumor surgical pathology and research

Contact Information

• jeff.simko@ucsf.edu
• Phone: (415) 353-7581
• Fax: (415) 353-7729

• 1600 Divisadero Street
• Room B620, Box 0506
• San Francisco, CA 94143