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Lab Manual for Moffitt-Long and Mount Zion

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Steve Miller, MD, PhD

Research and Clinical Interests

I am interested in the use of molecular methods for diagnosis and monitoring of clinical infectious disease, particularly in immunocompromised and transplant patients. Projects include:

  1. A collaborative translational effort to implement microarray diagnostics for identification and susceptibility of bacterial infections in septic patients.
  2. Clinical evaluation and implementation of quantitative PCR measurements of viral illness (EBV, BK, JC, CMV) and multiplex identification of these agents in disease or symptom-specific panels.
  3. Development and validation of an assay to diagnose and monitor T. cruzi-infected heart transplant candidates.

Selected Publications

  • Miller SA, Binder EM, Blackman MJ, Carruthers VB, Kim K. (2001) A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii. Journal of Biological Chemistry 276(48): 45341-8.
  • Miller S. (2002) The REMEDY Program: Recovery and donation of unused surgical supplies to developing countries. Einstein Quarterly Journal of Biology and Medicine 19(3): 121-4.
  • Miller SA, Rosario CL, Rojas E, Scorza JV. (2003) Intestinal parasitic infection and associated symptoms in children attending day care centres in Trujillo, Venezuela. Tropical Medicine and International Health 8(4): 342-7.
  • Miller SA. (2003) Subtilisin-like proteases TgSUB1 and TgSUB2 in Toxoplasma gondii: Involvement in specialized secretory organelles used for host cell invasion. Doctoral dissertation, Albert Einstein College of Medicine, Bronx, NY.
  • Miller SA, Thathy V, Ajioka JW, Blackman MJ, Kim K. (2003) TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. Molecular Microbiology 49(4):883-94.

Selected Awards

  • College of American Pathologists Foundation Scholar
Steve Miller, MD, PhD
  • Assistant Professor and Director, UCSF Clinical Laboratories at Mount Zion
  • Laboratory Medicine
  • Infectious Disease/Microbial Pathogenesis

Specialty Area

  • Molecular Microbiology

Contact Information

  • 1600 Divisadero St., Room B-232
  • San Francisco, CA 94115

Hospital Affiliation(s)

  • Mt. Zion

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