Gary A. Jarvis, PhD
Research and Clinical Interests
My research interests include: 1) Regulation of complement activation by blood-borne Gram-negative bacteria; 2) Development of vaccines for meningococcal meningitis and gonorrhea; 3) Complement deficiencies and susceptibility to bacterial sepsis; 4) Role of innate immune receptors in Gram-negative bacterial infections.
Selected Publications
- John, C. M., H. Leffler, B. Kahl-Knutsson, I. Svensson, and G. A. Jarvis. 2003. Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. Clin. Cancer Res. 9:2374-2383.
- Estabrook, M. E., D. L. Jack, N. J. Klein, and G. A. Jarvis. 2004. Mannose-binding lectin binds to two major outer membrane proteins, opacity protein and porin, of Neisseria meningitidis but not to lipooligosaccharide. J. Immunol. 172:3784-3792.
- Jarvis, G. A., E. N. Janoff, H. Cheng, D. Devita, C. Fasching, C. E. McCulloch, and E. L. Murphy. 2005. Human T lymphotropic virus type II infection and humoral responses to pneumococcal polysaccharide and tetanus toxoid vaccines. J. Infect. Dis. 191:1239-1244.
- Liu, X., A. Mosoian, T. L. Chang, B. Zerhouni-Layachi, A.Snyder, G. A. Jarvis, and M. E. Klotman. 2006. Gonococcal LOS suppresses HIV infection in human primary macrophages through induction of innate immunity. J. Infect. Dis. 194:751-759.
- Professor
- Laboratory Medicine
- Infectious Diseases
Specialty Area
- Gram-negative bacterial infections
Contact Information
- Gary.Jarvis@
ucsf.edu - Phone: (415) 221-4810, ext. 2303
- Fax: (415) 221-7542
- VA Medical Center,
- Dept. 111W1, 4150 Clement Street,
- San Francisco, CA 94121